21740-23-8

Basic information

• Product Name: 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose
• Synonyms: 3,5-bis[o-(p-chlorbenzoyl)]-alpha-D-ribofuranosyl chloride;1-Cl-3,5-bis-(4-cl-bz)- 2-deoxy-D-ribofuranose;1-Chloro-3,5-bis-(4-chlorobenzoyl)-2-deoxy-D-ribofuranose;[5-Chloro-2-[(4-chlorobenzoyl)oxymethyl]oxolan-3-yl] 4-chlorobenzoate;1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose;(4S,5R)-2-chloro-4-benzoyloxy-5-(benzoyloxymethyl)tetrahydrofuran;1-α-Chloro-3,5-di-O-(4-chlorobenzoyl) -2-deoxy-D-ribofuranose;(2R,3S,4R,5R)-5-Chloro-2-((4-chlorobenzoyloxy)methyl)-4-hydroxytetrahydrofuran-3-yl 4-chlorobenzoate
• CAS NO: 21740-23-8
• Molecular Formula: C₁₉H₁₅Cl₃O₅
• Molecular Weight: 429.68
• EINECS: 2017-001-1
• Product Categories: Bases & Related Reagents;Intermediates;Nucleotides
• Mol File: 21740-23-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 110-118°C (dec.)
• Boiling Point: 530.6 °C at 760 mmHg
• Flash Point: 193 °C
• Appearance: White solid
• Density: 1.46 g/cm³
• Vapor Pressure: 1.5E-19mmHg at 25°C
• Refractive Index: 1.636
• Storage Temp.: Hygroscopic, -20?C Freezer, Under Inert Atmosphere
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• Stability: Not stable in Solution
• CAS DataBase Reference: 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose(21740-23-8)
• EPA Substance Registry System: 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose(21740-23-8)

Safety Data

• Hazardous Substances Data: 21740-23-8(Hazardous Substances Data)

Usage

Chemical Properties

1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose is White Solid

Uses

Different sources of media describe the Uses of 21740-23-8 differently. You can refer to the following data:
1. Intermediate used in the synthesis of nucleotide analogs.Unstable in solution!
2. 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose is used in the synthesis of nucleotide analogs. Unstable in solution!

InChI:InChI=1/C19H15Cl3O6/c20-12-5-1-10(2-6-12)15(24)16(25)18(27)19(28,9-14(22)23)17(26)11-3-7-13(21)8-4-11/h1-8,16,18,25,27-28H,9H2/t16?,18-,19-/m1/s1

Upstream product

• 80339-59-9 methyl 3,5-dibenzoyloxy-2-deoxy-α-D-erythropentofuranoside 
• 122-01-0 4-chloro-benzoyl chloride 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 452-51-7 D-2-deoxyribose 

Downstream Products

• 307306-06-5 2,5-difluoro-1-[1-[2-deoxy-3,5-di-O-(p-chlorobenzoyl)-β-D-ribofuranosyl]]benzene 
• 307306-05-4 2,5-difluoro-1-[1-[2-deoxy-3,5-di-O-(p-chlorobenzoyl)-α-D-ribofuranosyl]]benzene 
• 445041-06-5 C₂₆H₂₃Cl₂N₂O₆⁽¹⁺⁾ 
• 444342-68-1 C₂₅H₂₁Cl₂N₂O₆⁽¹⁺⁾ 
• 174522-72-6 4-Amino-2-phenyl-8-[2-deoxy-3,5-di-O-(4-chlorobenzoyl)-β-D-ribofuranosyl]-pteridine-7-one 
• 1201639-52-2 4-N,N-dimethylaminomethyleneimino-6-phenyl-1-(3,5-di-O-4-chlorobenzoyl-2'-deoxy-β-D-erythro-pentofuranosyl)-7(8H)-pteridone 
• 1201639-53-3 4-N,N-dimethylaminomethyleneimino-6-phenyl-1-(3,5-di-O-4-chlorobenzoyl-2'-deoxy-α-D-erythro-pentofuranosyl)-7(8H)-pteridone 

Relevant articles and documents

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Synthesis and hybridization studies of oligonucleotide sequences with modified fluorescent nucleoside analogs

Two complementary oligodeoxynucleotide hexamers CATGAA and TTCATG and a pentamer with a fluorescent nucleoside analog viz. 9-N-(2'-deoxy-β-D- ribofuranosyl) carbazole (C*) incorporated into it, TTC*ATG were synthesized and characterised by spectroscopic and chromatographic studies. The comparative fluorescent studies of the two nucleoside analogs viz. 9-N- (2'-deoxy-β-D-ribofuranosyl) acridone and its carbazole analog (C*) have been carried out under different experimental conditions. The effect on fluorescence by incorporation of (C*) into the sequence and its subsequent hybridization with the complementary sequence have been studied.