174523-22-9

Upstream product

• 172161-51-2 N⁶-benzoyl-3'-O-tert-butyldimethylsilyl-2',5'-dideoxy-5'-thioadenosine 
• 133510-56-2 3'-O-(methylthiomethyl)thymidine 
• 174523-24-1 5'-S-acetyl-3'-O-methylthiomethyl-5'-deoxy-5'-thiothymidine 
• 129185-32-6 5'-O-(4,4'-dimethoxytrityl)-3'-O-(methylthiomethyl)thymidine 
• 172161-66-9 5'-S-acetyl-N⁶-benzoyl-3'-O-tert-butyldimethylsilyl-2',5'-dideoxy-5'-thioadenosine 
• 172161-63-6 5'-S-acetyl-N⁶-benzoyl-2',5'-dideoxy-5'-thioadenosine 
• 4546-72-9 N₆-benzoyl-2'-deoxyadenosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 174523-26-3 3'-O-methylene-5'-deoxy-5'-thiothymidylyl-(3'->5')-N⁶-benzoyl-3'-O-tert-butyldimethylsilyl-2',5'-dideoxy-5'-thioadenosine 

Relevant academic research and scientific papers

A versatile approach to the synthesis of oligonucleotide analogs containing neutral 5′-thioformacetal internucleoside linkages

Activation of nucleoside donors 5 by sulfuryl chloride followed by the addition of 5′-thionucleoside acceptors 3 yields 5′-thioformacetal dinucleotide analogs 6 with in situ trapping of liberated methanesulfenyl chloride with cyclohexene. Purine as well a