174535-84-3

Upstream product

• 1337883-11-0 C₁₄H₁₅N₃O₂S₂ 
• 16078-71-0 ethyl 5-amino-1-phenyl-1H-pyrazole-4-carboxylate 
• 198715-88-7 5-Amino-1-phenyl-1H-pyrazole-4-carboxylic acid [1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-hydrazide 
• 198715-89-8 5-Amino-1-phenyl-1H-pyrazole-4-carboxylic acid [1-(4-chloro-phenyl)-meth-(Z)-ylidene]-hydrazide 
• 110810-00-9 5-Amino-1-phenyl-1H-pyrazole-4-carboxylic acid [1-phenyl-meth-(E)-ylidene]-hydrazide 
• 58046-54-1 5-amino-1-phenyl-1H-pyrazole-4-carbohydrazide 
• 198716-01-7 1-Phenyl-6-thioxo-6,7-dihydro-1H-pyrazolo[3,4-d][1,3]thiazin-4-one 

Downstream Products

• 1337883-12-1 2-chloromethyl-8-phenylpyrazolo[3,4-d][1,3,4]thiadiazolo[3,2-a]pyrimidin-4(1H)-one 
• 1337883-19-8 2-[{(m-tolyl)amino}methyl]-8-phenylpyrazolo[3,4-d][1,3,4]thiadiazolo[3,2-a]pyrimidin-5(1H)-one 
• 1337883-20-1 2-[{(p-anisyl)amino}methyl]-8-phenylpyrazolo[3,4-d][1,3,4]thiadiazolo[3,2-a]pyrimidin-5(1H)-one 
• 1337883-13-2 2-[{(methyl)amino}methyl]-8-phenylpyrazolo[3,4-d][1,3,4]thiadiazolo[3,2-a]pyrimidin-5(1H)-one 
• 1337883-14-3 2-[{(ethyl)amino}methyl]-8-phenylpyrazolo[3,4-d][1,3,4]thiadiazolo[3,2-a]pyrimidin-5(1H)-one 
• 1337883-15-4 2-[{(hexyl)amino}methyl]-8-phenylpyrazolo[3,4-d][1,3,4]thiadiazolo[3,2-a]pyrimidin-5(1H)-one 
• 1337883-16-5 2-[{(furfuryl)amino}methyl]-8-phenylpyrazolo[3,4-d][1,3,4]thiadiazolo[3,2-a]pyrimidin-5(1H)-one 
• 1084955-55-4 3-(1-benzofuran-2-ylcarbonyl)-1,9-diphenyl-1,4-dihydro-6H-pyrazolo[3',4':4,5]-pyrimidino[1,2-b][1,2,4,5]tetrazin-6-one 
• 198716-02-8 1-Phenyl-5-{[1-phenyl-meth-(E)-ylidene]-amino}-6-thioxo-1,5,6,7-tetrahydro-pyrazolo[3,4-d]pyrimidin-4-one 

Relevant academic research and scientific papers

A novel and eco-friendly procedure for the synthesis of some pyrazolo-thiadiazolo-pyrimidinones and its in vitro anti-bacterial activity

A novel series of 2-substituted-aminomethyl-8-phenyl-pyrazolo[3,4-d][1,3,4] thiadiazolo[3,2-a]pyrimidin-4 (1H)-ones have been synthesized by treating 2-chloromethyl-8-phenyl-pyrazolo[3,4-d][1,3,4]thiadiazolo[3,2-a] pyrimidin-4(1H)-one with various nucleophiles. The chloromethyl derivative was prepared by treating 2-amino-3-mercapto pyrazolo[3,4-d]pyrimidine with one carbon donor, chloroacetic acid. The intermediate 2-amino-3-mercapto pyrazolo[3,4-d]pyrimidine was prepared by a novel, eco-friendly route starting from 2-amino-3-carbethoxy-1-phenyl-pyrazole. The target compounds exhibited broad-spectrum antibacterial activity (Kirby Bauer's Method). Springer Science+Business Media, LLC 2011.

Syntheis of Some New Pyrazolotriazines, Pyrazolothiazines and Pyrazolopyrimidines

When the pyrazole derivatives 3a,b were treated with triethyl orthoformate, the pyrazolotriazinethiones 5a,b were obtained.These were S-alkylated to give compounds 6a-d.Treatment of 5a,b with hydrazine hydrate in ethanol afforded 7,8 respectively.Benzylid