174543-80-7 Usage
Uses
Used in Pharmaceutical Industry:
(3R)-Amino-3-methyl-piperidine-1-carboxylic acid benzyl ester is used as a key intermediate in the synthesis of various drugs and biologically active molecules. Its unique structure allows for the development of pharmaceutical compounds with potential therapeutic applications, contributing to advancements in drug discovery and treatment options.
Used in Organic Synthesis:
In the field of organic synthesis, (3R)-Amino-3-methyl-piperidine-1-carboxylic acid benzyl ester serves as a suitable intermediate for the synthesis of other complex organic molecules. Its benzyl ester group plays a crucial role in facilitating the creation of diverse chemical entities, further expanding the scope of its applications in chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 174543-80-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,5,4 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 174543-80:
(8*1)+(7*7)+(6*4)+(5*5)+(4*4)+(3*3)+(2*8)+(1*0)=147
147 % 10 = 7
So 174543-80-7 is a valid CAS Registry Number.
174543-80-7Relevant academic research and scientific papers
On the Ritter reaction of cyclic hydroxyamines: Synthesis of conformationally-restricted reduced amide dipeptide isosteres
Taylor, G. Mark,Baker, Stewart J.,Gedney, Andrea,Pearson, David J.,Sibley, Graham E. M.
, p. 1297 - 1300 (2007/10/03)
The Ritter reactions of 3-alkyl-3-hydroxyazetidine or -piperidine derivatives give low yields of the desired products, whereas the 3-alkyl-3-hydroxy-pyrrolidine and 4-alkyl-4-hydroxy-piperidine derivatives react smoothly to give the corresponding acetamides. An alternative route to 3-acylamino-3-alkylpiperidines, which were designed as conformationally-restricted reduced amide dipeptide isosteres, was devised from nipecotic acid vai a Hofmann rearrangement.