174560-84-0

Upstream product

• 104-63-2 N-Benzylethanolamine 
• 106-89-8 epichlorohydrin 

Downstream Products

• 40987-25-5 N-benzyl-2-chloromethylmorpholine 
• 40987-53-9 4-benzyl-2-(toluene-p-sulphonyloxymethyl)morpholine 
• 40987-24-4 R,S-2-hydroxymethyl-4-benzylmorpholine 
• 943443-03-6 hexahydro-4-phenylmethyl-1,4-oxazepin-6-ol 

Relevant academic research and scientific papers

Concise synthesis of (S)-N-BOC-2-hydroxymethylmorpholine and (S)-N-BOC-morpholine-2-carboxylic acid

(Chemical Equation Presented) An operationally simple synthesis of N-BOC-2-hydroxymethylmorpholine (1) and N-BOC-morpholine-2-carboxylic acid (2) from epichlorohydrin has been developed. No chromatography is required in the processing, which allows high p

NOVEL PYRIMIDINE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL USE THEREOF AS AKT(PKB) PHOSPHORYLATION INHIBITORS

The present invention relates to novel chemical compounds derived from pyrimidines, to the method for preparing same, to the novel intermediates obtained, to the use thereof as drugs, to the pharmaceutical compositions containing same, and to the therapeutic use thereof as AKT inhibitors.

Efficient one-pot synthesis of enantiomerically pure 2-(hydroxymethyl)- morpholines

An efficient and convenient one-pot procedure for the synthesis of enantiomerically pure 2-(hydroxymethyl)morpholines with a widely variable substitution pattern was developed. Addition of chiral β-amino alcohols to (S)- or (R)-epichlorohydrin in the pres