174582-84-4

Upstream product

• 143-33-9 sodium cyanide 
• 174582-82-2 (4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-hydroxymethyloxazolidin-2-one 
• 183298-69-3 (4S,5S)-5-((1R)-1-benzoyloxy-2-propen-1-yl)-4-(p-toluenesulfonyloxy)-methyl-2-oxazolidinone 
• 99679-75-1 Methyl-4,6-O-benzyliden-2-desoxy-2-<(methoxycarbonyl)amino>-α-D-ribo-hexopyranosid-3-ulose 
• 174582-81-1 (4R,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-2-oxooxazolidin-4-carboxaldehyde 
• 174582-79-7 methyl 4,6-O-benzylidene-2-deoxy-2-(methoxycarbonylamino)-α-D-allopyranoside 
• 174582-80-0 methyl 2-amino-4-O-benzoyl-6-bromo-2,3-N,O-carbonyl-2,6-dideoxy-α-D-allopyranoside 

Downstream Products

• 183298-70-6 (4S,5S)-5-((1R)-1-benzoyloxy-2-propen-1-yl)-3-tert-butoxycarbonyl-4-cyanomethyl-2-oxazolidinone 

Relevant academic research and scientific papers

Syntheses of optically active, unusual, and biologically important hydroxy-amino acids from d-glucosamine

Manipulation of D-glucosamine as a chiral pool including stereoinversion of the C3-hydroxyl group, degradation of the C6-carbon, and/or one carbon homologation at the C1-position realized chiral syntheses of (2S,3S)-dihydroxy-(4S)-amino acid moieties, important structural components of a gastroprotective substance AI-77-B and a group of antitumor substances calyculins.

Chiral syntheses of dihydroxyamino acid moieties of AI-77-B and calyculins from D-glucosamine

Manipulation of cis (4S,5S)-4,5-disubstituted 2-oxazolidinones (4, 5), derived easily from D-glucosamine (1) as a chiral pool, including degradation of the C6-carbon and/or one-carbon homologation at the C1-position allowed chiral syntheses of (2S,3S)-dihydroxy-(4S)-amino acid moieties (6-8), which are important structural components of a gastroprotective substance, AI-77- B, and a group of antitumor substances, calyculins.