174583-84-7 Usage
Uses
Used in Pharmaceutical Industry:
Lafutidine Impurity B is used as a reference standard for the identification and quantification of impurities in the synthesis process of Lafutidine. It helps in ensuring the purity and quality of the final product, which is an important aspect in the pharmaceutical industry.
Used in Quality Control and Regulatory Compliance:
Lafutidine Impurity B is used as a reference material in quality control testing and regulatory compliance. It helps in the development and validation of analytical methods for the detection and quantification of impurities in Lafutidine, ensuring that the drug meets the required safety and efficacy standards.
Used in Research and Development:
Lafutidine Impurity B is used in research and development for the study of the synthesis process, impurity profiling, and optimization of the manufacturing process of Lafutidine. It aids in understanding the formation of impurities and their impact on the drug's efficacy and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 174583-84-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,5,8 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 174583-84:
(8*1)+(7*7)+(6*4)+(5*5)+(4*8)+(3*3)+(2*8)+(1*4)=167
167 % 10 = 7
So 174583-84-7 is a valid CAS Registry Number.
174583-84-7Relevant academic research and scientific papers
Synthetic method for Lafutidine oxide impurities
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Paragraph 0032; 0033; 0034; 0035; 0038; 0039, (2017/06/27)
The invention belongs to the technical field of chemistry and in particular relates to a synthetic method of Lafutidine oxide impurities, namely -2-[(2- furyl methyl) sulfonyl]-N-[4-[4-(1-piperidyl methyl)-2-pyridyl]oxygen-(Z)-2-butenyl] acetamide (formula I). The synthetic method mainly comprises the following steps: 2-(2-furfuryl sulfydryl)acetic acid-(4-nitrophenol) ester, namely the compound II is oxidized and then docked and refined with 4-[4-(N-piperidine methyl) pyridine-2-oxygen] cis-2-butene-1-amine, namely the compound IV to obtain oxide impurities of which the purity is more than 99.5%. The synthesized high-purity Lafutidine oxide impurities are taken as impurity standards for product inspection, thereby being beneficial to strengthening location and qualitativeness of the impurities so as to improve the quality control of Lafutidine active pharmaceutical ingredients.
