1746-32-3 Usage
Uses
Used in Pharmaceutical Industry:
[(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid is used as a key intermediate in the development of pharmaceuticals for [application reason] the treatment of diseases related to sialic acid metabolism. Its role in the biosynthesis of sialic acids makes it a promising candidate for therapeutic applications.
Used in Cancer Research:
In the field of cancer research, [(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid is used as a potential target for the development of anti-cancer drugs. Its involvement in the regulation of sialic acid production, which is often altered in cancer cells, makes it a valuable compound for investigating novel therapeutic strategies against cancer.
Used in Inflammation Research:
[(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid is also used in the research of anti-inflammatory drugs. Since sialic acids are known to play a role in immune response and inflammation, understanding the role of ManNAc-6P in their biosynthesis can lead to the development of new treatments for inflammatory conditions.
Used in Biochemical Research:
In the field of biochemical research, [(2R,3S,4R,5R)-5-acetamido-2,3,4-trihydroxy-6-oxo-hexoxy]phosphonic acid is utilized as a vital tool for studying the biosynthesis of sialic acids and their role in various biological processes. This knowledge can contribute to a better understanding of the underlying mechanisms of diseases and the development of targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1746-32-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,4 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1746-32:
(6*1)+(5*7)+(4*4)+(3*6)+(2*3)+(1*2)=83
83 % 10 = 3
So 1746-32-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H16NO9P/c1-3(10)9-5-7(12)6(11)4(18-8(5)13)2-17-19(14,15)16/h4-8,11-13H,2H2,1H3,(H,9,10)(H2,14,15,16)/t4-,5-,6-,7-,8+/m1/s1
1746-32-3Relevant academic research and scientific papers
Hydrophobic derivatives of 2-amino-2-deoxy-D-glucitol-6-phosphate: A new type of D-glucosamine-6-phosphate synthase inhibitors with antifungal action
Janiak, Agnieszka M.,Hoffmann, Maria,Milewska, Maria J.,Milewski, Slawomir
, p. 1653 - 1662 (2007/10/03)
Several N-acyl and ester derivatives of 2-amino-2-deoxy-D-glucitol-6-phosphate (ADGP) have been synthesised and tested as inhibitors of fungal enzymes involved in early steps of chitin biosynthesis and for antifungal activity. All the tested derivatives w
