17465-39-3Relevant academic research and scientific papers
Reaction of Oxazolines with Phosphorus Oxychloride
Dordor, Isabelle M.,Mellor, John M.,Kennewell, Peter D.
, p. 1253 - 1258 (2007/10/02)
The reaction of simple aryloxazolines with phosphorus oxychloride in pyridine affords aryl nitriles.Alcohols, obtained by the reaction of ortho-lithiated oxazolines with ketones, under similar conditions, typically give substituted aryl nitriles.Exceptionally, further reaction can afford substituted indenone derivatives.Alcohols obtained by the reaction of ortho-lithiated oxazolines with aryl aldehydes react with phosphorus oxychloride in pyridine to give products by cleavage of the oxazoline ring.
REACTION OF OXAZOLIN WITH PHOSPHORUS OXYCHLORIDE
Dordor, Isabelle M.,Mellor, John M.,Kennewell, Peter, D.
, p. 1437 - 1440 (2007/10/02)
Reaction of oxazolines with phosphorus oxychloride in pyridine gives nitriles and the value of the procedure is shown for substituted oxazolines obtained via addition of ortho-lithiated oxazolines to aldehydes and ketones.
