174676-82-5

Upstream product

• 171196-82-0 (S)-N-<3-ethoxycarbonyl-2(E)-propen-1-yl>-N-(1-phenyleth-1-yl)amine 
• 175287-54-4 [(3S,4R)-4-Benzenesulfonyl-5-oxo-1-((S)-1-phenyl-ethyl)-pyrrolidin-3-yl]-acetic acid methyl ester 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 173933-98-7 (3R,4R,1'S)-4-ethenyl-3-methoxycarbonyl-1-(1'-phenylet-1'-yl)pyrrolidin-2-one 
• 174676-80-3 (4R,1'S)-2-<2-oxo-1-(1'-phenyleth-1'-yl)pyrrolidin-4-yl>ethanol 
• 174758-50-0 (4S,1'S)-4-ethenyl-1-(1'-phenyleth-1'-yl)pyrrolidin-2-one 
• 173724-91-9 (S)-N-<2(E)-buten-1-yl>-N-(1-phenyleth-1-yl)methoxycarbonylacetamide 
• 162103-28-8 N-<(S)-1-phenyleth-1-yl>-N-<2(E)-buten-1-yl>amine 
• 175287-53-3 methyl (3R,4R,1'S)-[3-methoxycarbonyl-2-oxo-1-(1'-phenyleth-1'-yl)pyrrolidin-4-yl]acetate 
• 175287-50-0 (S)-N-<3-ethoxycarbonyl-2(E)-propen-1-yl>-N-(1-phenyleth-1-yl)benzenesulphonylacetamide 
• 175287-49-7 (S)-N-<3-ethoxycarbonyl-2(E)-propen-1-yl>-N-(1-phenyleth-1-yl)methoxycarbonylacetamide 
• 174676-81-4 methyl (4S,1'S)-<2-oxo-1-(1'-phenyleth-1'-yl)pyrrolidin-4-yl>acetate 

Downstream Products

• 122442-02-8 (S)-(+)-homo-β-proline 

Relevant academic research and scientific papers

Diastereomerically pure pyrrolidin-2-ones by intramolecular Michael reaction. Synthesis of both (S)- and (R)-3-pyrrolidineacetic acid

By intramolecular conjugate addition of their derived enolates, the amides 5 and 6 gave diastereomeric mixtures of pyrrolidin-2-ones 10,11 and 12,13, in good yield and 80:20 d.r. After chromatographic separation, the configuration of pure diastereomers wa

A convenient approach to diastereomerically pure 1,3,4-trisubstituted pyrrolidin-2-ones by intramolecular cyclisation of N-(2-alken-1-yl)amides mediated by Mn(III). An entry to both (R)- and (S)-3-pyrrolidineacetic acid

The oxidative cyclisation of a series of either (S)-N-(2-alken-1-yl)-N-(1-phenyleth-1-yl)-acetoacetamides 5a-d and methoxycarbonylacetamides 6a-b, performed by using Mn(OAc)3 · 2H2O and Cu(OAc)2 · H2O in acetic