175287-54-4

Upstream product

• 171196-82-0 (S)-N-<3-ethoxycarbonyl-2(E)-propen-1-yl>-N-(1-phenyleth-1-yl)amine 
• 3959-23-7 benzenesulfonylacetic acid 
• 186581-53-3 diazomethane 
• 175287-50-0 (S)-N-<3-ethoxycarbonyl-2(E)-propen-1-yl>-N-(1-phenyleth-1-yl)benzenesulphonylacetamide 

Downstream Products

• 174676-82-5 methyl (3S,1'S)-<1-(1'-phenyleth-1'-yl)-pyrrolidin-3-yl> acetate 
• 122442-02-8 (S)-(+)-homo-β-proline 
• 174676-81-4 methyl (4S,1'S)-<2-oxo-1-(1'-phenyleth-1'-yl)pyrrolidin-4-yl>acetate 

Relevant academic research and scientific papers

Diastereomerically pure pyrrolidin-2-ones by intramolecular Michael reaction. Synthesis of both (S)- and (R)-3-pyrrolidineacetic acid

By intramolecular conjugate addition of their derived enolates, the amides 5 and 6 gave diastereomeric mixtures of pyrrolidin-2-ones 10,11 and 12,13, in good yield and 80:20 d.r. After chromatographic separation, the configuration of pure diastereomers wa