174677-83-9

Basic information

• Product Name: (1S,2S)-N,N-Bis[2-(diphenylphosphino)benzyl]cyclohexane-1,2-diamine, min. 97%
• Synonyms: (1S,2S)-N,N-Bis[2-(diphenylphosphino)benzyl]cyclohexane-1,2-diamine, min. 97%;(1S,2S)-N,N-Bis[2-(diphenylphosphino)benzyl]cyclohexane-1,2-diaMine;S,S-N,N'-bis[[2-(diphenylphosphino) phenyl]Methyl]-1,2-CyclohexanediaMine;(1S,2S)-N1,N1-Bis(2-(diphenylphosphino)-benzyl)cyclohexane-1,2-diamine;(S,S)-1,2-Bis[[[2-(diphenylphosphino)phenyl]methyl]amino]cyclohexane;(1S,2S)-N,N'-Bis[[2-(diphenylphosphino)phenyl]methyl]-1,2-cyclohexanediamine;(1S,2S)-N,N'-Bis[[2-(diphenylphosphino)phenyl]methyl]- 1,2-cyclohexanediamine,99%e.e.
• CAS NO: 174677-83-9
• Molecular Formula: C₄₄H₄₄N₂P₂
• Molecular Weight: 662.781082
• Product Categories: Chiral Phosphine
• Mol File: 174677-83-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 54-56℃
• Boiling Point: 749.8±60.0 °C(Predicted)
• Appearance: yellow/solid
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.75±0.40(Predicted)
• Water Solubility: Insoluble in water.
• Sensitive: Air Sensitive
• CAS DataBase Reference: (1S,2S)-N,N-Bis[2-(diphenylphosphino)benzyl]cyclohexane-1,2-diamine, min. 97%(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-N,N-Bis[2-(diphenylphosphino)benzyl]cyclohexane-1,2-diamine, min. 97%(174677-83-9)
• EPA Substance Registry System: (1S,2S)-N,N-Bis[2-(diphenylphosphino)benzyl]cyclohexane-1,2-diamine, min. 97%(174677-83-9)

Safety Data

• Hazardous Substances Data: 174677-83-9(Hazardous Substances Data)

Usage

Uses

It is employed as a intermediate for pharmaceutical and asymmetirc synthesis.

Upstream product

• 50777-76-9 (2-formylphenyl)(diphenyl)phosphine 
• 21436-03-3 (S,S)-1,2-diaminocyclohexane 
• 174677-82-8 (S,S)-N,N'-bis[o-(diphenylphosphino)benzylidene]-1,2-diiminocyclohexane 

Relevant articles and documents

New chiral cationic rhodium-aminophosphine complexes for asymmetric transfer hydrogenation of aromatic ketones

The new chiral ligands (S,S)-N,N′-bis[o-(diphenylphosphino)benzylidene]1,2-diiminocyclohexane, [(S,S)-1] and (S,S)-N,N′-bis[o-diphenylphosphino]benzyl-1,2-diaminocyclohexane, [(S,S)-2] have been prepared. The interaction of [(S,S)-1] and [(S,S)-2] with [Rh(COD)Cl]2 afforded the corresponding cationic rhodium complexes [(S,S)-3][X] and [(S,S)-4][X] (X=PF6-, BF4- or ClO4-), respectively. [(S,S)-1], [(S,S)-2], [(S,S)-3][X] and [(S,S)-4][X] have been fully characterized by elemental analyses and spectroscopic methods. These chiral cationic rhodium complexes serve as catalytst precursors for the asymmetric transfer hydrogenation of acetophenone derivatives in 2-propanol and [(S,S)-4][PF6] acts as an excellent catalyst in the reduction of m-chloroacetophenone, giving the corresponding optical alcohols in 99% yield and up to 94% ee.