174698-36-3Relevant academic research and scientific papers
Inhibitors of farnesyl-protein transferase
-
, (2008/06/13)
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invent
Preparation of 3-amino-1,4-benzodiazepin-2-ones via direct azidation with trisyl azide
Butcher, John W.,Liverton, Nigel J.,Selnick, Harold G.,Elliot, Jason M.,Smith, Garry R.,Tebben, Andrew J.,Pribush, David A.,Wai, John S.,Claremon, David A.
, p. 6685 - 6688 (2007/10/03)
An efficient synthesis of 3-amino-1,4-benzodiazepin-2-ones utilizing triisopropylbenzenesulfonyl azide (trisyl azide) for the direct azidation of 1,4-benzodiazepin-2-ones is described.
