174718-95-7

Basic information

• Product Name: [Zn(C₂₅H₂₁N₄O₈)]⁽¹⁺⁾
• CAS NO: 174718-95-7
• Molecular Weight: 570.854
• Mol File: 174718-95-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [Zn(C₂₅H₂₁N₄O₈)]⁽¹⁺⁾(CAS DataBase Reference)
• NIST Chemistry Reference: [Zn(C₂₅H₂₁N₄O₈)]⁽¹⁺⁾(174718-95-7)
• EPA Substance Registry System: [Zn(C₂₅H₂₁N₄O₈)]⁽¹⁺⁾(174718-95-7)

Safety Data

• Hazardous Substances Data: 174718-95-7(Hazardous Substances Data)

Upstream product

• 1079893-79-0 streptonigrin 
• 54010-75-2 zinc trifluoromethanesulfonate 

Relevant articles and documents

A proton nuclear magnetic resonance study of the interaction of zinc(II) with the antitumour drug streptonigrin

The interaction of zinc(II) with the antitumour drug streptonigrin in [2H8]tetrahydrofuran has been studied by 400 MHz variable-temperature 1H NMR spectroscopy. At 190 K, and in the presence of an excess of zinc(II) trifluoromethanesulfonate (triflate) (10-15 equivalents), streptonigrin forms a 1:1 complex 1a (6%) and two diastereomeric 2:1 complexes, 1b (15%) and 1c (79%). The relative concentrations of these complexes are highly temperature dependent and at room temperature only 1a is detected. A fourth minor complex 1d was detected (3CN and less than 5 equivalents of zinc(II) triflate, 1a-1d are detected, but in the presence of 10-15 equivalents of zinc(II) triflate 1a is the predominant complex (> 93%) in the range 235-300 K. Implications for the role of metal ions in the mechanism of the antitumour action of streptonigrin are discussed.