174732-96-8

Basic information

• Product Name: N-Boc-3-hydroxy-DL-phenylalanine
• Synonyms: N-Boc-3-hydroxy-DL-phenylalanine;(Tert-Butoxy)Carbonyl DL-m-Tyr-OH;N-Boc-DL-3-hydroxy-Phenylalanine
• CAS NO: 174732-96-8
• Molecular Formula: C₁₄H₁₉NO₅
• Molecular Weight: 281.30436
• Mol File: 174732-96-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Boc-3-hydroxy-DL-phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-3-hydroxy-DL-phenylalanine(174732-96-8)
• EPA Substance Registry System: N-Boc-3-hydroxy-DL-phenylalanine(174732-96-8)

Safety Data

• Hazardous Substances Data: 174732-96-8(Hazardous Substances Data)

Usage

General Description

N-Boc-3-hydroxy-DL-phenylalanine is a chemical compound with the molecular formula C15H19NO5. It is a derivative of the amino acid phenylalanine, with an additional Boc (tert-butoxycarbonyl) protecting group attached to the nitrogen atom and a hydroxyl group attached to the carbon in the 3 position. N-Boc-3-hydroxy-DL-phenylalanine is commonly used in the synthesis of peptides and pharmaceuticals as a chiral building block. It is also utilized as a key intermediate in the manufacturing of various biologically active compounds. N-Boc-3-hydroxy-DL-phenylalanine is important in the field of medicinal chemistry and organic synthesis, as it allows for the controlled modification of phenylalanine and contributes to the development of new drugs and therapies.

Upstream product

• 775-06-4 D/L-3-hydroxy-phenylalanine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 325464-47-9 N-Boc-D,L-m-Tyr(O-2-Pyrim)-OH 
• 190905-50-1 methyl 2-(tert-butyloxycarbonylamino)-3-(3-methoxyphenyl)propanoate 
• 1015069-23-4 Propyl 2-[(tert-butoxy)carbonylamino]-3-(3-propoxyphenyl)propanoate 
• 1571933-52-2 C₂₄H₄₀INO₅Si 
• 1571933-94-2 C₁₈H₂₀INO₆S 
• 1571933-89-5 C₂₇H₃₆BrNO₈S 
• 1571933-90-8 C₂₇H₃₆BrNO₈S 
• 1571933-87-3 tert-butyl 2-(tert-butoxycarbonylamino)-3-(2-bromo-5-(2-(4-methylphenylsulfonyloxy)ethoxy)phenyl)propanoate 
• 1571933-84-0 C₁₈H₂₆BrNO₅ 
• 1571933-82-8 C₂₄H₄₀BrNO₅Si 
• 1571933-96-4 C₂₇H₄₉NO₅SiSn 
• 1571933-71-5 C₂₄H₄₀INO₅Si 
• 1571933-73-7 C₂₄H₄₀INO₅Si 
• 1571933-62-4 C₂₀H₂₉BrINO₅ 

Relevant articles and documents

AROMATIC AMINO ACID DERIVATIVE AND POSITRON EMISSION TOPOGRAPHY (PET) PROBE UTILIZING SAME

A compound having a structure represented by the general formula (I): (wherein n is 0 or 1; R1 represents a hydrogen atom (only if n = 0), a halogen atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, an optionally substituted amino group, an o

SUBSTITUTED HETEROCYCLIC COMPOUNDS

The present invention relates to substituted heterocyclic compounds of Formula I or XI: or pharmaceutically acceptable salts or N-oxides or quaternary ammonium salts thereof wherein constituent members are provided hereinwith, as well as their compositions and methods of use, which are histamine II4 receptor inhibitors useful in the treatment of histamine II4 receptor-associated conditions or diseases or disorders including, for example, inflammatory diseases or disorders, pruritus, and pain.

Synthesis of tyrosine-derived tetrahydroisoquinolines by Lewis acid catalyzed cyclization of N-(phenylsulfonyl)alkyloxazolidinones

N-Boc-protected tyrosine esters 5a,b were converted into tetrahydroisoquinolines 13 and 14 in four steps by reduction and ring closure to oxazolidinones 9 and 10, addition of benzenesulfinic acid and aldehydes to sulfones 11 and 12 and subsequent Lewis ac