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174740-80-8

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174740-80-8 Usage

General Description

1-[(4-methylphenyl)sulfonyl]-2-azetidinecarboxylic acid is a chemical compound with the molecular formula C13H15NO4S. It is a sulfonylazetidinecarboxylic acid derivative that contains an azetidine ring and a sulfonyl group. 1-[(4-methylphenyl)sulfonyl]-2-azetidinecarboxylic acid is of interest due to its potential pharmaceutical properties, as sulfonylazetidinecarboxylic acid derivatives have been investigated for their potential as antiviral and antitumor agents. The presence of the sulfonyl group makes it a valuable target for medicinal chemistry research, as sulfonyl groups are versatile functional groups that can be modified to alter the compound's properties. Further research is needed to explore the potential applications of 1-[(4-methylphenyl)sulfonyl]-2-azetidinecarboxylic acid in the development of new pharmaceutical drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 174740-80-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,7,4 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 174740-80:
(8*1)+(7*7)+(6*4)+(5*7)+(4*4)+(3*0)+(2*8)+(1*0)=148
148 % 10 = 8
So 174740-80-8 is a valid CAS Registry Number.

174740-80-8Relevant articles and documents

Inexpensive multigram-scale synthesis of cyclic enamines and 3-N spirocyclopropyl systems

Kumar, Pratik,Zainul, Omar,Laughlin, Scott T.

supporting information, p. 652 - 656 (2018/02/07)

Cyclic enamines are important synthons for many synthetic and pharmacological targets. Here, we report an inexpensive, catalyst-free, multigram-scale synthesis for cyclic enamines with exocyclic double bonds and four- to seven-membered rings. This strategy is more conducive to scale up, permissive of functionalization around the cyclic system, and less sensitive to the nature of the N-protecting group than previously-described methods for cyclic enamine synthesis. Further, we explore application of these enamines to the synthesis of highly-strained spirocyclic 3N-cyclopropyl scaffolds.

Enantiodivergent synthesis of N-protected azetidine-2-carboxylic acid

Biswas, Tanmoy,Mukherjee, Jyoti Prasad,Chattopadhyay, Shital K.

, p. 1416 - 1422,7 (2020/09/16)

A new route to both enantiomers of N-tosyl-azetidine-2- carboxylic acid has been developed from (R)-2-cyclohexylideneglyceraldehyde which proceeded with good overall yield and excellent enantiomeric purity.

Thermal Arndt-Eistert reactions of N-tosyl cyclic α-amino acids

Jin, Jing Yi,Wu, Xue,Tian, Guan Rong

, p. 2535 - 2541 (2007/10/03)

Thermal Arndt-Eistert reactions of N-tosyl cyclic α-amino acids were studied to explore the preparation of α,β-unsaturated esters bearing a terminal tosylamino group. For L-N-tosyl-aziridine 2-carboxylic acid and L-N-tosyl-azetidine 2-carboxylic acid, the corresponding (E)-α,β- unsaturated esters were obtained stereospecifically. Copyright Taylor & Francis, Inc.

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