174858-24-3Relevant academic research and scientific papers
The synthesis of (S)-3-acetylthio-2-benzylpropionic acid from (Z)-2-chloromethyl-3-phenylprop-2-enoic acid by asymmetric hydrogenation: A chiral building block of an enkephalinase inhibitor
Yuasa, Yoko,Yuasa, Yoshifumi,Tsuruta, Haruki
, p. 511 - 514 (2007/10/03)
(S)-2-Benzyl-3-chloropropionic acid (7) was synthesized from (Z)-2-(chloromethyl)-3-phenylprop-2-enoic acid (5) by asymmetric hydrogenation with a ruthenium 2,2′-bis(di-p-tolylphosphino)-1,1′-binaphthyl complex in the presence of triethylamine. Acetylthio
(S)-2-aralkyl-3-chloropropionic acid and process for the preparation thereof
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, (2008/06/13)
The present invention provides a novel 2-aralkyl-3-chloropropionic acid and a process for the preparation thereof. A novel 2-aralkyl-3-chloropropionic acid is represented by the general formula (1): STR1 and can be prepared by asymmetrically hydrogenating
