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Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, also known as Fmoc-protected tyrosine, is a chemical compound with the molecular formula C27H25NO5. It is a derivative of the amino acid tyrosine, featuring a 9H-fluoren-9-ylmethoxycarbonyl (Fmoc) protecting group. Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]is primarily used as a building block in the synthesis of peptides and proteins, playing a crucial role in biochemistry and pharmaceutical research.

174879-26-6

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  • 2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoic acid

    Cas No: 174879-26-6

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174879-26-6 Usage

Uses

Used in Peptide Synthesis:
Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]is used as a building block for the synthesis of peptides and proteins. The Fmoc protecting group allows for the selective deprotection and coupling of tyrosine residues during the stepwise assembly of peptide chains, facilitating the efficient and controlled synthesis of complex peptide structures.
Used in Biochemistry Research:
In the field of biochemistry, Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]is utilized as a reagent in various chemical reactions. Its Fmoc protecting group enables the controlled modification of peptides and proteins, allowing researchers to study the structure, function, and interactions of these biomolecules.
Used in Pharmaceutical Research:
Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]is widely used in pharmaceutical research for the development of peptide-based drugs and therapeutic agents. The Fmoc protecting group aids in the synthesis of bioactive peptides with specific pharmacological properties, contributing to the discovery of novel treatments for various diseases.
Used in Peptide Modification:
Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]is employed in the modification of peptides to improve their stability, solubility, and biological activity. The Fmoc protecting group allows for the selective introduction of functional groups, post-translational modifications, and other chemical modifications, enhancing the properties of peptide-based therapeutics.
Used in Organic Synthesis:
As a white to off-white powder that is soluble in organic solvents, Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]is also utilized in organic synthesis for the preparation of various chemical compounds and materials. Its unique structure and reactivity make it a valuable building block in the synthesis of complex organic molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 174879-26-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,8,7 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 174879-26:
(8*1)+(7*7)+(6*4)+(5*8)+(4*7)+(3*9)+(2*2)+(1*6)=186
186 % 10 = 6
So 174879-26-6 is a valid CAS Registry Number.

174879-26-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Fmoc-DL-Tyr-OH

1.2 Other means of identification

Product number -
Other names Fmoc-Tyr-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:174879-26-6 SDS

174879-26-6Relevant articles and documents

Useful reagents for introduction of Boc and Fmoc protective groups to amines: Boc-DMT and Fmoc-DMT

Hioki, Kazuhito,Kinugasa, Mizuho,Kishimoto, Michiko,Fujiwara, Miho,Tani, Shohei,Kunishima, Munetaka

, p. 1931 - 1933 (2007/10/03)

New amino-protecting reagents, Boc-DMT and Fmoc-DMT, were prepared, and found to be useful for the introduction of Boc and Fmoc groups into amines. Both the reagents can protect various amines including amino acids in good yield in aqueous media. Since the reagents are neither unstable nor irritating, they are practically useful. Georg Thieme Verlag Stuttgart.

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