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FMOC-DL-2-AMINOBUTYRIC ACID is a chemical compound that features a 2-aminobutyric acid molecule protected by a 9-fluorenylmethoxycarbonyl (FMOC) group. FMOC-DL-2-AMINOBUTYRIC ACID is integral in the field of peptide synthesis, where it acts as a building block for the incorporation of the 2-aminobutyric acid residue into peptides and proteins. The FMOC group's role as a protecting agent is crucial, enabling selective deprotection and coupling reactions during the synthesis process. The inclusion of the 2-aminobutyric acid in peptides and proteins can impart distinctive characteristics, rendering FMOC-DL-2-AMINOBUTYRIC ACID an essential tool in chemical biology, drug discovery, and protein engineering research.

174879-28-8

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174879-28-8 Usage

Uses

Used in Pharmaceutical and Biochemical Research:
FMOC-DL-2-AMINOBUTYRIC ACID is used as a synthetic building block for the creation of custom peptides and proteins. Its incorporation allows researchers to study the effects of specific amino acid sequences on protein function and stability.
Used in Chemical Biology:
FMOC-DL-2-AMINOBUTYRIC ACID is utilized as a component in the design of bioactive molecules, facilitating the exploration of protein-ligand interactions and the development of novel biological probes.
Used in Drug Discovery:
In the quest for new therapeutic agents, FMOC-DL-2-AMINOBUTYRIC ACID is employed as a key constituent in the synthesis of peptide-based drugs, potentially leading to the discovery of medicines with improved pharmacological properties.
Used in Protein Engineering:
FMOC-DL-2-AMINOBUTYRIC ACID is used as a modifying agent in protein engineering, enabling the alteration of protein properties such as folding, stability, and activity, which is vital for the creation of proteins with tailored functions for various applications.
Used in Peptide Synthesis Education:
FMOC-DL-2-AMINOBUTYRIC ACID serves as an educational tool in teaching laboratories, where students learn about the principles of peptide synthesis and the role of protecting groups in the process.

Check Digit Verification of cas no

The CAS Registry Mumber 174879-28-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,8,7 and 9 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 174879-28:
(8*1)+(7*7)+(6*4)+(5*8)+(4*7)+(3*9)+(2*2)+(1*8)=188
188 % 10 = 8
So 174879-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H19NO4/c1-2-17(18(21)22)20-19(23)24-11-16-14-9-5-3-7-12(14)13-8-4-6-10-15(13)16/h3-10,16-17H,2,11H2,1H3,(H,20,23)(H,21,22)/p-1/t17-/m1/s1

174879-28-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-α-Fmoc-norvaline

1.2 Other means of identification

Product number -
Other names 2-(9H-fluoren-9-ylmethoxycarbonylamino)-butyric acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:174879-28-8 SDS

174879-28-8Relevant academic research and scientific papers

Solid-phase synthesis of unnatural α-amino acid derivatives using a resin-bound glycine cation equivalent

O'Donnell, Martin J.,Delgado, Francisca,Drew, Mark D.,Pottorf, Richard S.,Zhou, Changyou,Scott, William L.

, p. 5831 - 5835 (1999)

Unnatural amino acids were synthesized on solid-phase by reaction of a resin-bound Schiff base with organoboranes. This novel use of a resin-bound glycine cation equivalent allows for the preparation of a variety of amino acid structural types not readily available by the complementary anionic equivalent.

Dehydration of threonine esters during tosylation

Somlai,Lovas,Forgo,Murphy,Penke

, p. 3633 - 3640 (2007/10/03)

Tosylation of N-α-protected threonine methyl-and benzyl esters was investigated. Depending on the protecting groups, the composition of the reaction mixtures showed different ratio between O-tosyl-and dehydrothreonine derivatives. The latter was formed ex

Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same

-

, (2008/06/13)

Compounds of the following general formula (I) and pharmaceutically acceptable salts thereof.

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