17494-19-8Relevant academic research and scientific papers
Oxidized isoquinolinoisoindolinone and benzazepinoisoindolinone alkaloids cores by convergent cyclisation processes: π-aromatic attack of thionium and oxonium species
Bousquet, Till,Fleury, Jean-Fran?ois,Da?ch, Adam,Netchita?lo, Pierre
, p. 706 - 715 (2007/10/03)
An efficient methodology for synthesis of isoindoloisoquinoline 5a and isoindolobenzazepine 5b in oxidized forms as tetracyclic alkaloids cores are reported from N-bromoethylphthalimide (6) or phthalic anhydride and 2-phenylthioethylamine (8) in a five- o
Selective Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. New 2,3-Dihydrothiazoloisoindol-5(9bH)-ones and Related Compounds with Anti-HIV-1 Activity
Mertens, Alfred,Zilch, Harald,Koenig, Bernhard,Schaefer, Wolfgang,Poll, Thomas,et al.
, p. 2526 - 2535 (2007/10/02)
A series of substituted 2,3-dihydrothiazoloisoindol-5(9bH)-ones and related compounds 1-73 were synthesized and evaluated for their ability to inhibit reverse transcriptase (RT) of the human immune deficiency virus 1 (HIV-1) and replication of HIV-
The Reaction of Arylmagnesium Bromides with N-(ω-Bromoalkyl)phthalimides
Braun, Loren L.,Xia, Jing,Cooney, Mark J.,Ahmed, Mohammed K.,Isaacson, Eugene I.
, p. 1441 - 1445 (2007/10/02)
The reaction of the N-(ω-bromoalkyl)phthalimides, 1 and 2, with a series of arylmagnesium bromides in tetrahydrofuran yielded the corresponding oxazoloisoindoles 4a-4h and oxazinoisoindoles 5a-5f.At low temperatures, phenylmagnesium bromide, on treatment
Synthesis and Reactions of 2,3-Dihydro-oxazoloisoindol-5(9bH)-ones
Wharton, Clifford J.,Wrigglesworth, Roger
, p. 809 - 814 (2007/10/02)
The synthesis and reactions with nucleophiles of 2,3-dihydro-oxazoloisoindol-5(9bH)-ones are described.
The Reaction of Lithium Phenylacetylide and Phenyllithium with N-(ω-Bromoalkyl)phthalimides
Torian, Bruce E.,Braun, Loren L.
, p. 293 - 295 (2007/10/02)
Lithium phenylacetylide reacted with short-chain N-(ω-bromoalkyl)phathalimides 1b and 1c to give tricyclic products 2b and 2c in moderate yields.Likewise, tricyclic products 3a-c were obtained when short-chain imides 1a-c were treated with phenyllithium.W
