174958-65-7Relevant academic research and scientific papers
Novel approach to the synthesis of aliphatic and aromatic α-keto acids
Balducci, Daniele,Conway, Philip A.,Sapuppo, Giulia,Müller-Bunz, Helge,Paradisi, Francesca
, p. 7374 - 7379 (2012)
A new practical and efficient synthesis of α-keto acids was accomplished starting from the synthon 1,4-diacetylpiperazine-2,5-dione. The synthesis encompasses both aromatic and aliphatic substrates proving to be versatile and innovative with excellent carbon economy and recycling of the glycine by-product.
