175023-42-4

Basic information

• Product Name: 1-benzyl-N-4-methoxyphenoxycarbonylpiperidine-4-amine
• CAS NO: 175023-42-4
• Molecular Weight: 340.422
• Mol File: 175023-42-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-N-4-methoxyphenoxycarbonylpiperidine-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-N-4-methoxyphenoxycarbonylpiperidine-4-amine(175023-42-4)
• EPA Substance Registry System: 1-benzyl-N-4-methoxyphenoxycarbonylpiperidine-4-amine(175023-42-4)

Safety Data

• Hazardous Substances Data: 175023-42-4(Hazardous Substances Data)

Upstream product

• 50541-93-0 4-amino-1-benzylpiperidine 
• 175023-51-5 4-methoxyphenyl 4-nitrophenyl carbonate 

Relevant articles and documents

Synthesis of symmetrical and unsymmetrical ureas using unsymmetrical diaryl carbonates

Appropriately substituted unsymmetrical diaryl carbonates react smoothly with primary amines to give the carbamates derived by nucleophilic displacement of the less electron rich aromatic substituent. Subsequent treatment of the carbamates with primary and secondary amines gives either symmetrical or unsymmetrical ureas in excellent yield and the overall process can be carried out as a 'one pot' operation. Acetonitrile is the preferred solvent and addition of DBU facilitates the carbamate → urea transformation.