17503-90-1Relevant articles and documents
A novel and efficient domino reaction for the one-pot synthesis of spiro-2-aminopyrimidinones
Ramezanpour, Sorour,Hashtroudi, Mehri Seyed,Bijanzadeh, Hamid Reza,Balalaie, Saeed
, p. 3980 - 3982 (2008)
A novel and efficient protocol is developed for the synthesis of various spiro-2-amino pyrimidinones via the three-component condensation of alkyl cyanoacetates, guanidinium carbonate and N-substituted 4-piperidinones in ethanol at reflux. High yields, neutral conditions, and short reaction times are advantages of this method.