175135-24-7 Usage
Uses
Used in Pharmaceutical Research:
2-(Propylthio)pyridine-3-carbonyl chloride is used as a reagent in pharmaceutical research for the synthesis of various organic compounds. Its strong and reactive nature as a carbonyl chloride allows for the creation of a wide range of pharmaceutical drugs and other organic molecules.
Used in Organic Synthesis:
In the field of organic synthesis, 2-(Propylthio)pyridine-3-carbonyl chloride is employed as a building block for the development of complex organic compounds. Its unique structure, including the propylthio group, provides specificity in its reactivity, making it a valuable component in the synthesis of specialized organic molecules.
Used in Drug Development:
2-(Propylthio)pyridine-3-carbonyl chloride is utilized in the development of pharmaceutical drugs due to its versatile and reactive properties. Its ability to form various organic compounds makes it a valuable asset in the creation of new and innovative medications for various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 175135-24-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,1,3 and 5 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 175135-24:
(8*1)+(7*7)+(6*5)+(5*1)+(4*3)+(3*5)+(2*2)+(1*4)=127
127 % 10 = 7
So 175135-24-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H10ClNOS/c1-2-6-13-9-7(8(10)12)4-3-5-11-9/h3-5H,2,6H2,1H3
175135-24-7Relevant academic research and scientific papers
Discovery of a potent, selective, and orally bioavailable acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor: Discovery of 2-[(3 s)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]- 3-piperidyl]acetic acid (AZD4017)
Scott, James S.,Bowker, Suzanne S.,Deschoolmeester, Joanne,Gerhardt, Stefan,Hargreaves, David,Kilgour, Elaine,Lloyd, Adele,Mayers, Rachel M.,McCoull, William,Newcombe, Nicholas J.,Ogg, Derek,Packer, Martin J.,Rees, Amanda,Revill, John,Schofield, Paul,Selmi, Nidhal,Swales, John G.,Whittamore, Paul R. O.
experimental part, p. 5951 - 5964 (2012/08/07)
Inhibition of 11β-HSD1 is an attractive mechanism for the treatment of obesity and other elements of the metabolic syndrome. We report here the discovery of a nicotinic amide derived carboxylic acid class of inhibitors that has good potency, selectivity, and pharmacokinetic characteristics. Compound 11i (AZD4017) is an effective inhibitor of 11β-HSD1 in human adipocytes and exhibits good druglike properties and as a consequence was selected for clinical development.
