175136-20-6 Usage
General Description
4-(3,4-Dichlorobenzyloxy)-3-nitrobenzaldehyde is a chemical compound with the molecular formula C14H9Cl2NO4. It is a pale yellow solid that is primarily used as an intermediate in the manufacture of pharmaceuticals. 4-(3,4-DICHLOROBENZYLOXY)-3-NITROBENZALDEHYDE is known for its nitro and chloro functional groups, making it useful in organic synthesis and as a building block for more complex molecules. It is also used in research and development for its unique properties and potential applications in various industries. However, it should be handled with care due to its potential health hazards and should only be used by trained professionals in controlled laboratory settings.
Check Digit Verification of cas no
The CAS Registry Mumber 175136-20-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,1,3 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 175136-20:
(8*1)+(7*7)+(6*5)+(5*1)+(4*3)+(3*6)+(2*2)+(1*0)=126
126 % 10 = 6
So 175136-20-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H9Cl2NO4/c15-11-3-1-10(5-12(11)16)8-21-14-4-2-9(7-18)6-13(14)17(19)20/h1-7H,8H2
175136-20-6Relevant articles and documents
Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558
Takano, Rieko,Yoshida, Masao,Inoue, Masahiro,Honda, Takeshi,Nakashima, Ryutaro,Matsumoto, Koji,Yano, Tatsuya,Ogata, Tsuneaki,Watanabe, Nobuaki,Hirouchi, Masakazu,Kimura, Takako,Toda, Narihiro
, p. 5546 - 5565 (2015/11/11)
GPR40 agonists stimulate insulin secretion only under the presence of high glucose concentration. Based on this mechanism, GPR40 agonists are believed to be promising novel insulin secretagogues with low risk of hypoglycemia. The optimizations of 3-aryl-3-ethoxypropanoic acids were performed to improve in vitro activity. We discovered compound 29r (DS-1558), (3S)-3-ethoxy-3-(4-{[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]oxy}phenyl)propanoic acid, which was confirmed to have an enhancing effect on glucose-dependent insulin secretion after intravenous glucose injection in SD rats.
