175153-39-6Relevant academic research and scientific papers
AMINO-PYRROLOPYRIMIDINONE COMPOUNDS AND METHODS OF USE THEREOF
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Paragraph 00571; 00574, (2018/03/25)
The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (
4,4-DIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE DERIVATIVES OR SALTS THEREOF
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Page 19; 21, (2008/06/13)
4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivatives, which have excellent arginine vasopressin V2 activity and are useful for a drug for the treatment of central diabetes insipidus and/or nocturia.
Benzoheterocyclic derivatives
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Page column 117, (2010/01/21)
A benzoheterocyclic derivative of the following formula [1]: and pharmaceutically acceptable salts thereof, which show excellent anti-vasopressin activity, vasopressin agonistic activity and oxytocin antagonistic activity, and are useful as a vasopressin antagonist, vasopressin agonist or oxytocin antagonist.
Novel design of nonpeptide AVP V2 receptor agonists: Structural requirements for an agonist having 1-(4-aminobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine as a template
Kondo,Ogawa,Shinohara,Kurimura,Tanada,Kan,Yamashita,Nakamura,Hirano,Yamamura,Mori,Tominaga,Itai
, p. 4388 - 4397 (2007/10/03)
The discovery of a series of nonpeptide arginine vasopressin V2 receptor agonists is described. After identifying the aniline derivative 8 as our lead compound from the metabolites of compound 7 that showed antidiuretic activity by po administr
