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6-(2,2,2-TRIFLUOROETHOXY)NICOTINIC ACID is a chemical compound derived from nicotinic acid, featuring a trifluoroethoxy group attached at the 6-position of the pyridine ring. This modification enhances the compound's lipophilicity and can influence its chemical and biological properties, making it a valuable building block in organic synthesis and drug discovery research.

175204-90-7

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175204-90-7 Usage

Uses

Used in Organic Synthesis:
6-(2,2,2-TRIFLUOROETHOXY)NICOTINIC ACID is used as a building block in organic synthesis for the creation of various complex organic molecules. The trifluoroethoxy group provides unique reactivity and properties that can be exploited in the synthesis of pharmaceuticals and other organic compounds.
Used in Drug Discovery Research:
In the pharmaceutical industry, 6-(2,2,2-TRIFLUOROETHOXY)NICOTINIC ACID is used as an intermediate in drug discovery research. Its unique structure and properties make it a promising candidate for the development of new drugs with potential therapeutic applications.
Used as a Potential Drug Candidate:
6-(2,2,2-TRIFLUOROETHOXY)NICOTINIC ACID may be used as a potential drug candidate for the treatment of various diseases. Its enhanced lipophilicity and altered chemical and biological properties could contribute to its efficacy in treating specific conditions, although further research and development are required to explore its therapeutic potential.
Used in Structure-Activity Relationship Studies:
6-(2,2,2-TRIFLUOROETHOXY)NICOTINIC ACID serves as a useful tool in the study of the structure-activity relationships of related compounds. By examining the effects of the trifluoroethoxy group on the compound's properties and activity, researchers can gain insights into the design of more effective and selective drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 175204-90-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,0 and 4 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 175204-90:
(8*1)+(7*7)+(6*5)+(5*2)+(4*0)+(3*4)+(2*9)+(1*0)=127
127 % 10 = 7
So 175204-90-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H6F3NO3/c9-8(10,11)4-15-6-2-1-5(3-12-6)7(13)14/h1-3H,4H2,(H,13,14)

175204-90-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(2,2,2-trifluoroethoxy)pyridine-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:175204-90-7 SDS

175204-90-7Downstream Products

175204-90-7Relevant academic research and scientific papers

ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS

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Page/Page column 107, (2012/05/05)

The present invention relates to arylamide derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channels are involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which voltage gated sodium channels are involved.

INDOLYLMETHYL-MORPHOLINE DERIVATIVES AS KINASE INHIBITORS

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Page/Page column 57-58, (2010/12/31)

A series of morpholine derivatives, substituted in the 4-position by a substituted carbonyl or sulfonyl moiety, and in the 3-position by an optionally substituted indol-3-ylmethyl group, being selective inhibitors of PI3 kinase enzymes, are accordingly of

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