175205-33-1 Usage
General Description
2-(Trifluoromethoxy)phenyl isothiocyanate is a chemical compound that belongs to the family of isothiocyanates, which are known for their diverse chemical and biological properties. It is derived from the substitution of a hydrogen atom with a trifluoromethoxy group on the phenyl ring. 2-(TRIFLUOROMETHOXY)PHENYL ISOTHIOCYANATE is widely used in organic synthesis as a reagent in the preparation of various biologically active molecules, including pharmaceuticals and agrochemicals. Its unique structure and functional group make it a valuable building block for the synthesis of complex organic compounds. Additionally, 2-(trifluoromethoxy)phenyl isothiocyanate has shown promising antiproliferative and antifungal activities, making it an important chemical for research and development in medicinal chemistry and pharmaceutical sciences.
Check Digit Verification of cas no
The CAS Registry Mumber 175205-33-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,0 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 175205-33:
(8*1)+(7*7)+(6*5)+(5*2)+(4*0)+(3*5)+(2*3)+(1*3)=121
121 % 10 = 1
So 175205-33-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H4F3NOS/c9-8(10,11)13-7-4-2-1-3-6(7)12-5-14/h1-4H
175205-33-1Relevant articles and documents
TRICYCLIC INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION
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Page/Page column 55; 56, (2012/06/01)
This invention relates to tricycle I and its therapeutic and prophylactic uses, wherein the variables C1, C2, Z1, Z2, Q, J, R1, and R3 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.
2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: Orally bioavailable compounds
Kai, Hiroyuki,Morioka, Yasuhide,Tomida, Minoru,Takahashi, Tadashi,Hattori, Maki,Hanasaki, Kohji,Koike, Katsumi,Chiba, Hiroki,Shinohara, Shunji,Kanemasa, Toshiyuki,Iwamoto, Yuka,Takahashi, Kohji,Yamaguchi, Yoshitaka,Baba, Takahiko,Yoshikawa, Takayoshi,Takenaka, Hideyuki
, p. 3925 - 3929 (2008/02/11)
Structure-activity relationships and efforts to optimize the pharmacokinetic profile of a class of 2-arylimino-5,6-dihydro-4H-1,3-thiazines as cannabinoid receptor agonists are described. Among the compounds examined, compound 14 showed potent affinity and high selectivity for CB2, and compound 23 showed potent affinities against CB1 and CB2. These compounds displayed oral bioavailability.
