175229-87-5 Usage
Uses
Used in Pharmaceutical Industry:
5-Quinolinamine,8-fluoro-(9CI) is used as an intermediate for organic synthesis, particularly in the preparation of pyridoquinolinones and pyridoquinolinecarboxylates. These compounds are known for their bactericidal properties, making them valuable in the development of new antibiotics and antimicrobial agents. The application of 5-Quinolinamine,8-fluoro-(9CI) in this context is aimed at addressing the growing need for novel and effective treatments against drug-resistant bacterial infections.
Used in Chemical Research:
In addition to its pharmaceutical applications, 5-Quinolinamine,8-fluoro-(9CI) is also utilized as a reagent in chemical research. Its unique structure allows for further functionalization and modification, enabling the synthesis of a wide range of chemical compounds with diverse properties and potential applications. This makes it a valuable tool for chemists and researchers working on the development of new materials, catalysts, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 175229-87-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,2 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 175229-87:
(8*1)+(7*7)+(6*5)+(5*2)+(4*2)+(3*9)+(2*8)+(1*7)=155
155 % 10 = 5
So 175229-87-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H7FN2/c10-7-3-4-8(11)6-2-1-5-12-9(6)7/h1-5H,11H2
175229-87-5Relevant academic research and scientific papers
Dual stimulatory and inhibitory effects of fluorine-substitution on mutagenicity: An extension of the enamine epoxide theory for activation of the quinoline nucleus
Saeki, Ken-Ichi,Kawai, Hiroshi,Kawazoe, Yutaka,Hakura, Atsushi
, p. 646 - 650 (2007/10/03)
Nineteen mono- and di-fluorinated derivatives of quinoline, 1,7- phenanthroline, 1,10-phenanthroline, benzo-[h]quinoline, and benzo[f]quinoline were subjected to analysis of their structure-mutagenicity relationships. For this purpose, six new fluorinated derivatives were synthesized. The results support that the enamine epoxide structure of the pyridine moiety, as well as the bay-region epoxide structure, is responsible for mutagenicity. Formation of K-region epoxides might involve a detoxification process rather than mutagenic activation.
