175234-79-4Relevant academic research and scientific papers
On-line solid phase synthesis of oligonucleotide-peptide hybrids using silica supports
Truffert, Jean-Christophe,Lorthioir, Olivier,Asseline, Ulysse,Thuong, Nguyen T.,Brack, Andre
, p. 2353 - 2356 (1994)
A procedure for the preparation of oligonucleotide-peptide hybrid molecules by means of automated synthesis is desribed.The conjugates have been assembled on silica support including CPG (Controlled Pore Glass) and Fractosil supports.The novel Nε/su
Fluorescent xDNA nucleotides as efficient substrates for a template-independent polymerase
Jarchow-Choy, Sarah K.,Krueger, Andrew T.,Liu, Haibo,Gao, Jianmin,Kool, Eric T.
, p. 1586 - 1594 (2011)
Template independent polymerases, and terminal deoxynucleotidyl transferase (TdT) in particular, have been widely used in enzymatic labeling of DNA 3′-ends, yielding fluorescently-labeled polymers. The majority of fluorescent nucleotides used as TdT subst
Synthesis, purification and characterization of two peptide-oligonucleotide conjugates as potential artificial nucleases
Truffert, Jean-Christophe,Asseline, Ulysse,Brack, Andre,Thuong, Nguyen T.
, p. 3005 - 3016 (1996)
Two peptide-oligonucleotide conjugates 10a and 10b, containing as their peptide moiety the active site mimic of ribonuclease A (HGH motif) and the Cu (II) complexing metallopeptide (GGH motif) respectively, have been synthesized by original on-line solid
Libraries of composite polyfluors built from fluorescent deoxyribosides
Gao, Jianmin,Straessler, Christoph,Tahmassebi, Deborah,Kool, Eric T.
, p. 11590 - 11591 (2007/10/03)
We report on a new class of water-soluble fluorescent molecules (polyfluors) that are composed of multiple individual fluorophores assembled on a DNA-like backbone. Four fluorophore deoxyribosides were synthesized, and these individual molecules were asse
