175278-47-4 Usage
General Description
The chemical compound 2-[4-(tert-butyl)phenoxy]-5-nitrobenzaldehyde is a nitroaromatic compound with a benzaldehyde structure. It has a nitro group and a tert-butyl substituent attached to a phenoxy group, which are both electron withdrawing groups. 2-[4-(TERT-BUTYL)PHENOXY]-5-NITROBENZALDEHYDE is often used in organic synthesis and in the production of pharmaceuticals, dyes, and other fine chemicals. It is also known for its potential as a building block for the synthesis of various biologically active compounds. The presence of the nitro and phenoxy functionalities provides this compound with interesting reactivity and potential uses in different chemical reactions and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 175278-47-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,7 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 175278-47:
(8*1)+(7*7)+(6*5)+(5*2)+(4*7)+(3*8)+(2*4)+(1*7)=164
164 % 10 = 4
So 175278-47-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H17NO4/c1-17(2,3)13-4-7-15(8-5-13)22-16-9-6-14(18(20)21)10-12(16)11-19/h4-11H,1-3H3
175278-47-4Relevant articles and documents
Nitroarylhydroxymethylphosphonic acids as inhibitors of CD45
Beers, Scott A.,Malloy, Elizabeth A.,Wu, Wei,Wachter, Michael P.,Gunnia, Uma,Cavender, Druie,Harris, Crafford,Davis, Janet,Brosius, Ruth,Pellegrino-Gensey, J. Lee,Siekierka, John
, p. 2203 - 2211 (2007/10/03)
A series of nitroarylhydroxymethylphosphonic acids was synthesized and evaluated as inhibitors of CD45. It was discovered that both the alpha hydroxy and nitro groups are essential for activity. Potency is enhanced by the addition of a large lipophilic group on the aryl ring adjacent to the phosphonic acid moiety. Kinetics studies have shown that these compounds are competitive inhibitors and thus bind at the active site of this enzyme.