175347-03-2

Upstream product

• 4405-28-1 2-(dimethylamino)-5-nitrobenzoic acid 
• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 17417-09-3 2-fluoro-5-nitrobenzonitrile 
• 7304-32-7 2-fluoro-5-nitrobenzoic acid 

Downstream Products

• 915394-38-6 dimethyl-(4-nitro-2-oxazol-2-yl-phenyl)-amine 
• 915394-39-7 N₁,N₁-dimethyl-2-oxazol-2-yl-benzene-1,4-diamine 
• 915394-37-5 N-(2,2-dimethoxyethyl)-2-dimethylamino-5-nitro benzamide 
• 175347-11-2 2-Dimethylamino-5-nitrophenyl isocyanate 
• 175347-06-5 2-Dimethylamino-5-nitrobenzoyl azide 

Relevant academic research and scientific papers

Discovery of novel 2-phenylamino-4-prolylpyrimidine derivatives as TRK/ALK dual inhibitors with promising antitumor effects

In order to explore novel TRK and ALK dual inhibitors, a series of 2-phenylamino-4-prolylpyrimidine derivatives were designed, synthesized and evaluated for their in vitro cytotoxicity and enzymatic activities. Delightfully, most compounds were detected m

ANTIFUNGAL AGENTS

Compounds of formula (I), and pharmaceutically acceptable salts thereof, may be used in therapy, for example as antifungal agents: (I) wherein: Rl, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. Certain compounds of formula (I) are also provided. Compounds of formula (T), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.

Decomposition of 2-dialkylaminobenzoyl azides to yield isocyanates and 1,1 -dialky lindazol-1-ium-3-olates

Substituted benzoyl azides normally yield the correspondingly substituted isocyanates but when a dialkylated amino group is in the 2-position, in addition to the isocyanate, the 1,1-dialkylated indazol-1-ium-3-olate is produced. The ratio of the two products is very variable depending upon the substitution in the benzene ring. Largest yields of the zwitterionic products were found when there was a substituent in the 3-position regardless of whether the substituent was electron-donating or -withdrawing.