175416-53-2Relevant articles and documents
An efficient entry to optically active anti- and syn-β-amino-α- trifluoromethyl alcohols
Fustero, Santos,Albert, Laia,Acena, Jose Luis,Sanz-Cervera, Juan F.,Asensio, Amparo
, p. 605 - 608 (2008/09/16)
The reaction of chiral 5,6-dihydro-2H-1,4-oxazin-2-ones with TMSCF 3 in the presence of a suitable activator leads to trifluoromethyl lactols, which can be selectively reduced to anti-β-amino-α- trifluoromethyl alcohols. The corresponding syn d