175418-41-4

Upstream product

• 186581-53-3 diazomethane 
• 175287-49-7 (S)-N-<3-ethoxycarbonyl-2(E)-propen-1-yl>-N-(1-phenyleth-1-yl)methoxycarbonylacetamide 
• 171196-82-0 (S)-N-<3-ethoxycarbonyl-2(E)-propen-1-yl>-N-(1-phenyleth-1-yl)amine 

Downstream Products

• 174676-79-0 methyl (3R,1'S)-<1-(1'-phenyleth-1'-yl)-pyrrolidin-3-yl> acetate 
• 122442-01-7 (R)-(-)-3-pyrrolidineacetic acid 
• 174676-78-9 methyl (4R,1'S)-<2-oxo-1-(1'-phenyleth-1'-yl)pyrrolidin-4-yl>acetate 

Relevant academic research and scientific papers

Diastereomerically pure pyrrolidin-2-ones by intramolecular Michael reaction. Synthesis of both (S)- and (R)-3-pyrrolidineacetic acid

By intramolecular conjugate addition of their derived enolates, the amides 5 and 6 gave diastereomeric mixtures of pyrrolidin-2-ones 10,11 and 12,13, in good yield and 80:20 d.r. After chromatographic separation, the configuration of pure diastereomers wa