175437-92-0

Basic information

• Product Name: 1-benzyl-N-(4-bromophenyl)piperidin-4-amine
• Synonyms: 1-benzyl-N-(4-bromophenyl)piperidin-4-amine
• CAS NO: 175437-92-0
• Molecular Formula: C₁₈H₂₁BrN₂
• Molecular Weight: 345.27674
• Mol File: 175437-92-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-benzyl-N-(4-bromophenyl)piperidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-N-(4-bromophenyl)piperidin-4-amine(175437-92-0)
• EPA Substance Registry System: 1-benzyl-N-(4-bromophenyl)piperidin-4-amine(175437-92-0)

Safety Data

• Hazardous Substances Data: 175437-92-0(Hazardous Substances Data)

Upstream product

• 106-40-1 4-bromo-aniline 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 220317-16-8 (1-benzyl-piperidin-4-ylidene)-(4-bromo-phenyl)-amine 

Relevant articles and documents

A new series of M3 muscarinic antagonists based on the 4-amino-piperidine scaffold

A series of 4-amino-piperidine containing molecules have been synthesized and structure-affinity relationship toward the M3-muscarinic receptor has been investigated. Chemical modulations provided molecules with Ki for the human M3-R up to 1 nM with variable selectivity (3- to 40-fold) over the human M2-R. Compounds 2 (pA2=8.3, 8.6) demonstrates in vitro on guinea pig bladder and ileal strips potent anticholinergic properties and tissue selectivity.