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175442-03-2

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175442-03-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 175442-03-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,4,4 and 2 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 175442-03:
(8*1)+(7*7)+(6*5)+(5*4)+(4*4)+(3*2)+(2*0)+(1*3)=132
132 % 10 = 2
So 175442-03-2 is a valid CAS Registry Number.

175442-03-2Relevant articles and documents

Reduced flexibility analogs of analgesic and cognition enhancing α-tropanyl esters

Manetti, Dina,Romanelli, Maria Novella,Bartolini, Alessandro,Dei, Silvia,Ghelardini, Carla,Gualtieri, Fulvio,Matucci, Rosanna,Scapecchi, Serena,Teodori, Elisabetta

, p. 105 - 111 (2007/10/02)

A series of semirigid analogs of compounds 1 and 2, two potent analgesics and cognition enhancers, have been synthesized and tested for antinociceptive activity (hot plate test) and for muscarinic affinity (binding in rat cerebral cortex). They were found to be in a general less potent than the reference compounds; only one of them (22) shows a good affinity for the muscarinic receptor and an antinociceptive efficacy comparable with those of the reference compounds. At a dose of 30 mg/kg 22 is also able to reverse the amnesic effect of dicyclomine. Since the analgesic effect of these compounds is affected by the 5-HT4 antagonist SDZ 205557, the possible role of this receptor is discussed.

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