175467-68-2

Basic information

• Product Name: 1-Phenyl-3-trimethylsilyl-2-azetidinethione
• CAS NO: 175467-68-2
• Molecular Weight: 235.425
• Mol File: 175467-68-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Phenyl-3-trimethylsilyl-2-azetidinethione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-3-trimethylsilyl-2-azetidinethione(175467-68-2)
• EPA Substance Registry System: 1-Phenyl-3-trimethylsilyl-2-azetidinethione(175467-68-2)

Safety Data

• Hazardous Substances Data: 175467-68-2(Hazardous Substances Data)

Upstream product

• 5099-95-6 1-phenylazetidin-2-one 
• 75-77-4 chloro-trimethyl-silane 
• 175467-62-6 1-Phenyl-azetidine-2-thione 

Downstream Products

• 175467-78-4 3-Isopropylidene-1-phenyl-2-azetidinethione 

Relevant articles and documents

3-Alkylidene-2-azetidinethiones: Useful intermediates for the synthesis of 3-substituted 2-azetidinethiones

3-Lithiated 2-azetidinethiones 1 were allowed to react with carbonyl compounds to give 3-(1-hydroxyalkyl)-2-azetidinethiones 3, 4 which were converted into α,β-unsaturated β-thiolactams 7, 8, 10 by elimination procedures. Alternatively, the title compounds were prepared by Peterson olefination of 3-trimethylsilyl-2-azetidinethiones 9. Reactions of 7, 8, 10 with thiophenol or sodium diethyl malonate provided the Michael adducts 11. E/Z, Photoisomerization of 7, 8 by visible light was observed. On deprotonation, 7a, 8a underwent allyl rearrangement to 13. VCH Verlagsgesellschaft mbH, 1996.