175468-07-2

Upstream product

• 175786-61-5 (S)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-pent-4-enoic acid ethyl ester 
• 175892-46-3 (2S,3S)-1,2-O-isopropylidene-3-vinylpentane-1,2,5-triol 
• 175468-06-1 (2S,3S)-5-O-benzoyl-1,2-O-isopropylidene-3-vinylpentane-1,2,5-triol 
• 98-88-4 benzoyl chloride 
• 175468-22-1 (2S,3S)-5-O-benzoyl-1-O-tert-butyldimethylsilyl-3-vinylpentane-1,2,5-triol 

Downstream Products

• 175468-08-3 (2R,3S)-1-O-acetyl-2-azido-5-O-benzoyl-3-vinylpentane-1,5-diol 

Relevant academic research and scientific papers

Synthesis of enantiopure 1,2-didehydropyrrolidine, D-proline, and oxazoline derivatives via Staudinger-aza-Wittig cyclization of γ-azido aldehydes

The synthesis of 3-, 3,5- and 3,4,5-substituted prolines 1 and oxazolines 3 from inexpensive D-mannitol, employing the Staudinger-aza-Wittig cyclization as a key step, is described.