175469-67-7

Upstream product

• 108-93-0 cyclohexanol 
• 10378-06-0 2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)[1,2-d]-2-oxazoline 
• 21559-72-8 cyclohexyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 175469-69-9 N-{(4aR,6R,7R,8R,8aS)-6-Cyclohexyloxy-8-[(3aR,4S,6S,7S,7aR)-7-(2-hydroxy-ethoxy)-2,2,4-trimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-6-yloxy]-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl}-acetamide 
• 624738-12-1 (R)-4-{(S)-2-[(R)-2-((4aR,6R,7R,8R,8aS)-7-Acetylamino-6-cyclohexyloxy-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyric acid benzyl ester 
• 500768-01-4 (R)-4-{(S)-2-[(R)-2-((2R,3R,4R,5S,6R)-3-Acetylamino-2-cyclohexyloxy-5-hydroxy-6-hydroxymethyl-tetrahydro-pyran-4-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyric acid benzyl ester 
• 500768-00-3 cyclohexyl 2-(acetylamino)-2-deoxy-4,6-O-isopropylidene-3-O-[(R)-1-carboxyethyl]-β-D-glucopyranoside 

Relevant academic research and scientific papers

N-Acetylmuramyl-L-Alanyl-D-Isoglutamine Glycosides: Effect of Glycoside Bond Configuration and Aglycone on Biological Activity

Hexyl, octyl, and cyclohexyl β-glycosides and heptyl and cyclohexyl α-glycosides of muramyl dipeptide (MDP) were synthesized. Tests in vitro and in vivo revealed lower immunostimulating activities of MDP α-glycosides in comparison with the corresponding β-glycosides and MDP itself. In the case of alkyl β-glycosides, differences in hydrocarbon chain lengths (C4-C8) and in aglycone (aliphatic chain and aliphatic or aromatic ring) exerted no substantial effect on the immunostimulating activity.

EXPEDITIOUS SYNTHESIS OF A TRISUBSTRATE ANALOGUE FOR α(1->3)FUCOSYLTRANSFERASE

The synthesis of cyclohexyl 2-acetamido-2-deoxy-3-O--α-L-fucopyranosyl)-β-D-glucopyranoside (1), a potential inhibitor of α(1->3)fucosyltransferases, is described.Target compound 1 was assembled via fucosylation of