17559-71-6Relevant academic research and scientific papers
Cis-trans Isomerization of Styrylpyrroles by Stray Light
Lee, Chang, Kiu,Yu, Ji Sook,Kim, Young Hie
, p. 345 - 348 (2007/10/02)
A series of substituted N-methylstyrylpyrroles (H, p-Br, p-CN, o,p-diCl,m-CH3, m-CN, m-NO2) were prepared via the Wittig reaction of 1-methylpyrrole-2-carboxaldehyde and substituted benzyltriphenylphosphonium bromides.Both cis and trans isomers were found to be present in the reaction mixture and they were separable by column chromatography in a few cases (H, p-Br, m-CN, m-NO2).Photochemical isomerizations of cis-styrylpyrroles to trans isomers were observed when the substituents were o,p-diCl and m-NO2, while the opposite was the case with compounds having H, p-Br, m-CH3, m-CN.It was difficult to separate the cis and trans mixture of p-cyanostyrylpyrroles and the equilibrium ratio did not change under similar photochemical reaction conditions.
