175656-40-3Relevant academic research and scientific papers
THE REACTION OF THE ACETATES OF α-CHLORO METHYL HEMIACETALS WITH NUCLEOPHILES. SYNTHESIS OF 2-HYDROXY-1,4-DITHIANES
Antolini, Luciano,Bellesia, Franco,Ghelfi, Franco,Pagnoni, Ugo M.,Pinetti, Adriano
, p. 11 - 18 (2007/10/03)
The acetates of the methyl hemiacetals of α-halo aldehydes, 1, easily undergo nucleophilic attack by lithium thiolates or ethane dithiolate affording α-thioalkyl aldehydes 2 or 2-hydroxy-1,4-dithianes 3, respectively, 3-monosubstituted dithianes 3 smoothl
Stereocontrolled synthesis of E-homoallylic sulfides with 1,4,5 related chiral centres using the [2,3] sigmatropic rearrangement of sulfonium ylides
Hartley, Richard C.,Richards, Ian C.,Warren, Stuart
, p. 359 - 376 (2007/10/03)
E-Homoallylic sulfides with 1,4,5 related chiral centres have been synthesised in a stereocontrolled way. An aldol condensation sets up the stereochemistry. Lactonisation with 1,2 arylsulfanyl migration followed by reduction and sulfur-assisted dehydratio
