175671-63-3Relevant academic research and scientific papers
Development of the Julia asymmetric epoxidation reaction. Part 1. Application of the oxidation to enones other than chalcones
Lasterra-Sanchez, M. Elena,Felfer, Ulfried,Mayon, Patrick,Roberts, Stanley M.,Thornton, Steven R.,Todd, Christine J.
, p. 343 - 348 (1996)
Asymmetric epoxidation of a variety of enones 3, 6, 8, 10, 12, 14, 16, 18, 21, 22, 26, 28-30 and 36 gives the corresponding oxiranes in good to excellent yield and optical purity. The oxidation medium consists of basic peroxide or sodium perborate or sodi
Julia-Colonna asymmetric epoxidation reactions under non-aqueous conditions: Rapid, highly regio- and stereo-selective transformations using a cheap, recyclable catalyst
Allen, Joanne V.,Bergeron, Sophie,Griffiths, Matthew J.,Mukherjee, Shubhasish,Roberts, Stanley M.,Williamson, Natalie M.,Wu, L. Eduardo
, p. 3171 - 3179 (2007/10/03)
The asymmetric oxidation of some enones (Table 1), selected dienones 3-5, and a trienone 13 is accomplished using poly-L-leucine or poly-D-leucine and urea hydrogen peroxide under non-aqueous conditions. One of the resultant epoxy ketones 6 has been converted into the δ-lactones 19 and 22.
Stereoselective epoxidation of electron poor dienes using poly(L-leucine)
Allen, Joanne V.,Cappi, Michael W.,Kary, Pierre D.,Roberts, Stanley M.,Williamson, Natalie M.,Wu, L. Eduardo
, p. 3297 - 3298 (2007/10/03)
Poly(L-leucine) catalysed oxidation of dienes 2, 3, 10, 16 and 18 and the triene 17 furnishes the corresponding epoxides 4, 5, 11, 19, 21 and 20 respectively in good to excellent yield and in states of high optical purity. Some regioselective reactions of the saturated epoxy ketones 5 and 11 are described.
