175477-55-1

Upstream product

• 104-55-2 3-phenyl-propenal 
• 93-08-3 methyl 2-naphthyl ketone 
• 14371-10-9 (E)-3-phenylpropenal 
• 893-33-4 4,4,4-trifluoro-1-(2-naphthyl)-1,3-butanedione 

Downstream Products

• 175671-63-3 Naphthalen-2-yl-[(2S,3R)-3-((E)-styryl)-oxiranyl]-methanone 
• 175671-62-2 Naphthalen-2-yl-[(2R,3S)-3-((E)-styryl)-oxiranyl]-methanone 
• 216689-33-7 (2S,3S,4S,5R)-(+)-2,3-epoxy-4,5-dihydroxy-5-phenyl-1-(2-naphthyl)pentan-1-one 
• 200615-37-8 [(2R,3S)-3-((4S,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-oxiranyl]-naphthalen-2-yl-methanone 
• 200615-39-0 (R)-3-((4R,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-3-hydroxy-1-naphthalen-2-yl-propan-1-one 
• 216689-49-5 (2R,3R,4R,5S)-(-)-2,3-epoxy-4,5-dihydroxy-5-phenyl-1-(2-naphthyl)pentan-1-one 
• 216689-48-4 (2R,3R,4S,5R)-(-)-2,3-epoxy-4,5-dihydroxy-5-phenyl-1-(2-naphthyl)pentan-1-one 
• 216689-32-6 (2S,3S,4R,5S)-(+)-2,3-epoxy-4,5-dihydroxy-5-phenyl-1-(2-naphthyl)pentan-1-one 
• 216689-34-8 [(2R,3S)-3-((4R,5S)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-oxiranyl]-naphthalen-2-yl-methanone 
• 216689-35-9 (R)-3-((4S,5S)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-3-hydroxy-1-naphthalen-2-yl-propan-1-one 
• 1438403-27-0 (3R,4E)-3-methyl-1-(naphthalen-2-yl)-5-phenylpent-4-en-1-one 

Relevant academic research and scientific papers

One-pot synthesis of cinnamylideneacetophenones and their in vitro cytotoxicity in breast cancer cells

A series of cinnamylideneacetophenones were synthesized via a modified Claisen-Schmidt condensation reaction and evaluated for cytotoxicity against breast cancer cells using the Alamar Blue assay. Derivatives 17 and 18 bearing a 2-nitro group on the B rin

Microwave-assisted convenient synthesis of α,β-unsaturated esters and ketones via aldol-adduct elimination

Various fluorinated 3-oxo ester/1,3-diketones were reacted with carbonyl compounds, in presence of piperidine and under microwave irradiation, to afford (E)-α,β-unsaturated esters and ketones in good yields. The systematic study reveals that the reaction proceeded through the formation of aldol adduct. The method provides a new and simple way for C,C bond formations. Copyright

Copper-catalyzed asymmetric 1,4-conjugate addition of Grignard reagents to linear α,β,γ,δ-unsaturated ketones

A highly regioselective and enantioselective copper-catalyzed 1,4-conjugate addition of Grignard reagents to linear α,β,γ,δ- unsaturated ketones was developed. The 1,4-addition products were obtained regioselectively in high yields with up to 98% ee. The Royal Society of Chemistry 2013.

Julia-Colonna asymmetric epoxidation reactions under non-aqueous conditions: Rapid, highly regio- and stereo-selective transformations using a cheap, recyclable catalyst

The asymmetric oxidation of some enones (Table 1), selected dienones 3-5, and a trienone 13 is accomplished using poly-L-leucine or poly-D-leucine and urea hydrogen peroxide under non-aqueous conditions. One of the resultant epoxy ketones 6 has been converted into the δ-lactones 19 and 22.