175477-55-1Relevant articles and documents
One-pot synthesis of cinnamylideneacetophenones and their in vitro cytotoxicity in breast cancer cells
Weldon, David J.,Saulsbury, Marilyn D.,Goh, Joshua,Rowland, Leah,Campbell, Petreena,Robinson, Laijia,Miller, Calvin,Christian, Joshua,Amis, Louisa,Taylor, Nia,Dill, Cassandra,Davis Jr., Willie,Evans, Stanley L.,Brantley, Eileen
, p. 3381 - 3384 (2014/07/22)
A series of cinnamylideneacetophenones were synthesized via a modified Claisen-Schmidt condensation reaction and evaluated for cytotoxicity against breast cancer cells using the Alamar Blue assay. Derivatives 17 and 18 bearing a 2-nitro group on the B rin
Microwave-assisted convenient synthesis of α,β-unsaturated esters and ketones via aldol-adduct elimination
Suman, Pathi,Nageswara Rao, Rayala,China Raju, Bhimapaka
, p. 1548 - 1559 (2013/09/02)
Various fluorinated 3-oxo ester/1,3-diketones were reacted with carbonyl compounds, in presence of piperidine and under microwave irradiation, to afford (E)-α,β-unsaturated esters and ketones in good yields. The systematic study reveals that the reaction proceeded through the formation of aldol adduct. The method provides a new and simple way for C,C bond formations. Copyright