175696-40-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 72856-90-7 ¹³C₁-acetic formic anhydride 
• 175696-39-6 4-(tert-Butyl-dimethyl-silanyloxy)-2,6-dimethyl-phenylamine 

Downstream Products

• 175696-45-4 C₄₇⁽¹³⁾CH₈₇NO₄Si₂ 
• 175696-41-0 13C-labeled 4-(t-butyldimethylsiloxy)-2,6-xylyl isocyanide 

Relevant academic research and scientific papers

Regio- and stereoselective incorporation of a13C nuclide into D-ribo-phytosphingosine via SmI2-mediated C-C formation with13C-labeled isocyanide

Preparation of a 13C-labeled isocyanide and its application to the total synthesis of [2-13C]D-ribo-C18-phytosphingosine are described. The synthesis of the labeled phytosphingosine is based on the use of the isocyanide as a 13CH-NH2 precursor in the SmI2-mediated three-component coupling reaction, wherein regio- and stereoselective incorporation of a 13C nuclide in the carbon skeleton is achieved.