175696-72-7Relevant academic research and scientific papers
Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors
Pensa, Anthony V.,Cinelli, Maris A.,Li, Huiying,Chreifi, Georges,Mukherjee, Paramita,Roman, Linda J.,Martásek, Pavel,Poulos, Thomas L.,Silverman, Richard B.
supporting information, p. 7146 - 7165 (2017/09/07)
Neuronal nitric oxide synthase (nNOS) is a target for development of antineurodegenerative agents. Most nNOS inhibitors mimic l-arginine and have poor bioavailability. 2-Aminoquinolines showed promise as bioavailable nNOS inhibitors but suffered from low
The antiinfluenza activity of pyrrolo[2,3-d]pyrimidines
Sznaidman, Marcos L.,Meade, Eric A.,Beauchamp, Lilia M.,Russell, Stuart,Tisdale, Margaret
, p. 565 - 568 (2007/10/03)
From a group of pyrrolo[2,3-d]pyrimidine compounds that have been screened against influenza virus, one derivative, 4-(3-piperidinyl benzylamino)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine (9), has shown promising activity against both the A and B strains. The
