175791-64-7

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 90057-09-3 2,4-dimethoxy-7H-pyrrolo<2,3-d>pyrimidine 
• 52898-49-4 4,N-dimethoxy-N-methylbenzamide 
• 155826-83-8 2,4-Dimethoxy-7-phenylsulfonylpyrrolo<2,3-d>pyrimidin-6-yl 4-methoxyphenyl ketone 
• 175791-63-6 6--2,4-dimethoxy-7-phenylsulfonylpyrrolo<2,3-d>pyrimidine 
• 155826-81-6 2,4-Dimethoxy-7-phenylsulfonylpyrrolo<2,3-d>pyrimidine 

Downstream Products

• 175791-65-8 5-Iodo-2,4-dimethoxypyrrolo<2,3-d>pyrimidin-6-yl 4-methoxyphenyl ketone 
• 132160-44-2 6-(4-hydroxybenzoyl)-5-(4-hydroxyphenyl)-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione 
• 175791-66-9 2,4-Dimethoxy-5-(4-methoxyphenyl)pyrrolo<2,3-d>pyrimidine-6-yl 4-methoxyphenyl ketone 

Relevant academic research and scientific papers

Condensed heteroaromatic ring systems. Part 24. Synthesis of rigidin, a pyrrolo[2,3-d]pynmidine marine alkaloid

The marine alkaloid rigidin has been synthesized from 2,4-dimethoxy-7-phenylsulfonylpyrrolo[2,3-d]-pyrimidine. Lithiation of the pyrrolo[2,3-d]pyrimidine followed by electrophilic substitution with N,4-dimethoxy-N-methylbenzainide afforded a 6-(4-methoxy)

TOTAL SYNTHESIS OF A MARINE ALKALOID, RIGIDIN

Rigidin, a marine alkaloid, was synthesized by the combination of acylation via lithiation and arylation by palladium-catalyzed reaction starting from 2,4-dimethoxypyrrolopyrimidine.