175792-72-0

Usage

Chemical Class

Imidazole

Molecular Structure

1H-Imidazole, 4,5-dihydro-4-phenyl-1-(phenylmethyl)

Stereochemistry

(R)-enantiomer

Functional Groups

Imidazole ring, phenyl group, methyl group

Potential Uses

Antifungal, antiparasitic, and development of new medications for various medical conditions

Importance

Unique structure and potential therapeutic properties of interest to researchers and pharmaceutical companies.

Upstream product

• 122-51-0 orthoformic acid triethyl ester 
• 155220-77-2 (R)-N¹-benzyl-1-phenylethane-1,2-diamine 

Downstream Products

• 175893-23-9 (3R,5R,7S,7aR)-1-benzyl-5,7-bis(tert-butoxycarbonyl)-3-phenylhexahydropyrrolo[1,2-a]imidazole 
• 175893-20-6 (3R,5R,7S,7aR)-dimethyl 1-benzyl-7-methyl-3-phenylhexahydro-1H-pyrrolo[1,2-a]imidazole-5,7-dicarboxylate 
• 175893-21-7 (3R,5R,7S,7aR)-1-benzyl-5-tert-butoxycarbonyl-7-methoxycarbonyl-7-methyl-3-phenylhexahydropyrrolo[1,2-a]imidazole 
• 175893-22-8 (3R,5R,7S,7aR)-1-benzyl-5-tert-butoxycarbonyl-7-cyano-7-methyl-3-phenylhexahydropyrrolo[1,2-a]imidazole 
• 1262797-06-7 (3R,5R,7R,7aS)-1-benzyl-5,7-bis(t-butoxycarbonyl)-3-phenylhexahydropyrrolo[1,2-a]imidazole 
• 1262797-10-3 (3R,5R,7R,7aS)-1-benzyl-5-t-butoxycarbonyl-7-cyano-7-methyl-3-phenylhexahydropyrrolo[1,2-a]imidazole 
• 1262797-09-0 (3R,5R,7R,7aS)-1-benzyl-7-cyano-5-methoxycarbonyl-7-methyl-3-phenylhexahydropyrrolo[1,2-a]imidazole 
• 1320285-81-1 C₃₂H₄₀N₂O₈ 
• 1320285-76-4 C₃₆H₃₀N₄O₄ 
• 1320285-74-2 C₂₆H₂₆N₄O₄ 

Relevant academic research and scientific papers

Cycloaddition of homochiral dihydroimidazoles: A 1,3-dipolar cycloaddition route to optically active pyrrolo[1,2-a]imidazoles

N-Alkylation of optically active 1-benzyl-4-phenyl-4,5-dihydroimidazole with active alkyl halides and treatment of the so-formed 4,5-dihydroimidazolium ions with DBU in the presence of a range of electron-deficient alkene dipolarophiles, constitutes a 'on

Cycloaddition of homochiral imidazolinium ylides: A route to optically active pyrroloimidazoles

The synthesis of either enantiomer of 1-benzyl-4-phenyl-2-imidazoline from phenylglycine is described. 'One-pot' generation and enantioselective 1,3-dipolar cycloaddition of homochiral azomethine ylides prepared from these imidazolines with a range of alkene dipolarophiles affords optically active hexahydropyrroloimidazole adducts.