175877-06-2Relevant academic research and scientific papers
Synthesis of α-(2 → 5)Neu5Gc oligomers
Ren, Chien-Tai,Chen, Chien-Sheng,Yu, Yi-Ping,Tsai, Yow-Fu,Lin, Ping-Yu,Chen, Yu-Ju,Zou, Wei,Wu, Shih-Hsiung
, p. 1085 - 1095 (2007/10/03)
A facile synthesis of the sialic acid oligomers α-(2 → 5)NeuSGc (1) is presented. Monosaccharides 2-4 with suitable functionality were used as the building blocks. After selective removal of the paired carboxyl and amine protecting groups, the fully prote
Synthesis of a sialic acid dimer derivative, 2′α-O-benzyl Neu5Ac-α-(2→5)Neu5Gc
Ren, Chien-Tai,Chen, Chien-Sheng,Wu, Shih-Hsiung
, p. 1376 - 1379 (2007/10/03)
The preparation of a disaccharide 2, Neu5Ac-α-(2→5)Neu5Gc having a α-benzyl protecting group at the reducing end, by the coupling of the easily accessible building units 4 and 5 is described. Subsequent deprotection of the coupling adduct led to the isolation of the target compound 2 in high yield.
