402948-44-1

Upstream product

• 100-51-6 benzyl alcohol 
• 402948-43-0 methyl (phenyl 4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-5-(2,2,2-trichloroethoxycarbonylamino)-D-glycero-β-D-galacto-2-nonulopyranosid)onate 
• 402948-42-9 methyl [phenyl 5-(2,2,2-trichloroethoxycarbonylamino)-3,5-dideoxy-2-thio-β-D-glycero-D-galacto-2-nonulopyranosid]onate 
• 367922-37-0 (2R,4S,5R,6R)-5-Amino-4-hydroxy-2-phenylsulfanyl-6-((1R,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 118977-25-6 methyl (phenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycerol-β-D-galactonon-2-ulopyranoside)onate 

Downstream Products

• 402948-39-4 methyl {2-benzyl-5-glycolylamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-5-O_glycolyl-[methyl (5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosyl)onate]-α-D-glycero-D-galacto-2-nonulopyranosid}onate 
• 552831-63-7 C₄₉H₆₄N₂O₂₈ 
• 552831-48-8 C₄₅H₆₀N₂O₂₅ 
• 175877-06-2 methyl [benzyl 5-amino-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosid]onate 
• 552831-51-3 C₄₈H₆₁Cl₃N₂O₂₇ 

Relevant academic research and scientific papers

Synthesis of α-(2 → 5)Neu5Gc oligomers

A facile synthesis of the sialic acid oligomers α-(2 → 5)NeuSGc (1) is presented. Monosaccharides 2-4 with suitable functionality were used as the building blocks. After selective removal of the paired carboxyl and amine protecting groups, the fully prote

Synthesis of a sialic acid dimer derivative, 2′α-O-benzyl Neu5Ac-α-(2→5)Neu5Gc

The preparation of a disaccharide 2, Neu5Ac-α-(2→5)Neu5Gc having a α-benzyl protecting group at the reducing end, by the coupling of the easily accessible building units 4 and 5 is described. Subsequent deprotection of the coupling adduct led to the isolation of the target compound 2 in high yield.