175881-65-9Relevant academic research and scientific papers
Asymmetric synthesis of chiral spirocyclanes: A new route to the optically active spiro[cyclopentane-1,1′-indan]-2,5-dione system
Kita, Yasuyuki,Kitagaki, Shinji,Imai, Reiko,Okamoto, Sachi,Mihara, Sachiko,Yoshida, Yutaka,Akai, Shuji,Fujioka, Hiromichi
, p. 1817 - 1820 (1996)
A new route to the optically pure spiro[cyclopentane-1,1′-indan]-2,5-dione system, which is supposed to be valuable for the asymmetric synthesis of optically active fredericamycin A, has been developed through a stereospecific rearrangement of the trans-α
Enantioselective total synthesis of a potent antitumor antibiotic, fredericamycin A
Kita,Higuchi,Yoshida,Iio,Kitagaki,Ueda,Akai,Fujioka
, p. 3214 - 3222 (2007/10/03)
The asymmetric total synthesis of both enantiomers of the potent antitumor antibiotic fredericamycin A (1) is detailed based on the protocol for the construction of its peri-hydroxy polyaromatic skeleton bearing the chirality at the spiro carbon via a str
